Clinical Pathology

Blood Bank

Information about Autologous (Self-donated) Donations and Transfusions, Directed Donations and Outpatient Transfusions.

Central Receiving

Information about the processing of specimens at the Fletcher Allen Laboratory.


The Chemistry laboratory performs a wide range of testing, including general chemistry, endocrine testing, tumor markers, therapeutic drug monitoring, limited toxicology, lead testing, hepatitis testing, protein electrophoresis and immunofixation, hemoglobin electrophoresis, special chemistry and urinalysis.

Compliance Support

The Laboratory Compliance Specialists are responsible for ensuring that the Department of Pathology and Laboratory Medicine is compliant with the laws and governing regulations promulgated by all appropriate federal and state regulating agencies.


The Cytogenetics Laboratory at Fletcher Allen is a full service laboratory. Computerized chromosome analysis and fluorescence in situ hybridization (FISH) analysis are available for testing amniotic fluids, peripheral or cord bloods, bone marrows, solid tumor biopsies, fine needle aspirates and tissues (products of conception, fascia, skin). FISH analysis is a new technology using fluorescent dye labeled DNA probes to look for specific chromosome abnormalities, both structural and numerical.

Examples of constitutional abnormalities that the laboratory has tested for include Williams Syndrome, DiGeorge Syndrome, Velo-CardioFacial Syndrome and Prader-Willi Syndrome. We have studied translocations and rearrangements of interest to oncologists such as Philadelphia chromosome, t(9;22) in CML or ALL, the t(15;17) in APL and the inv(l6) in AML. New probes are constantly being introduced to the market.

Hematology and Coagulation

The services provided by the Hematology and Coagulation departments include basic quantitative hematology testing, advanced coagulation tests for diagnosis and treatment and Bone Marrow diagnosis and consultation services.


Clinical Microbiology serves as the primary reference lab for our region. We offer testing in all areas of Microbiology including Bacteriology, Anaerobic Bacteriology, Mycology, Mycobacteriology, Parasitology, Virology and Chlamydia testing.


The phlebotomy team draws blood from about 225 inpatients and about 300 outpatients daily. These patients range from newborns to the elderly, from healthy young people to the chronically ill.