Fletcher Allen, a Vermont university hospital and medical center, serves all of
Vermont and the northern New York region. Located in Burlington, Fletcher Allen is a regional, academic healthcare center and teaching hospital in alliance with the University of Vermont.
Russell Silver Syndrome (RSS)
National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Russell Silver Syndrome (RSS) is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
- Russell Syndrome
- Silver Syndrome
- Silver-Russell Syndrome
- Russell-Silver Dwarfism
- Silver-Russell Dwarfism
Russell-Silver syndrome (RSS) is a rare genetic disorder characterized by a wide variety of symptoms. RSS is genetically heterogeneous, meaning that different genetic abnormalities are believed to cause the disorder. RSS is characterized by a wide spectrum of symptoms and physical findings that vary in range and severity from case to case. The characteristic findings are growth delays before birth (prenatal or intrauterine growth retardation) and after birth (postnatal growth deficiency). Growth deficiency often results in short stature in adulthood. Additional common symptoms include unusual, distinctive facial features, a pinky that is fixed or 'locked' in a bent position (clinodactyly), and undergrowth of one side or structure of the body (hemihypotrophy), resulting in unequal (asymmetric) growth. Many children with RSS have normal intelligence, but rowing evidence suggests that there is an increased risk of learning disabilities. In most cases, the exact underlying genetic cause of RSS is not known.
Human Growth Foundation
997 Glen Cove Avenue
Glen Head, NY 11545
6645 W. North Avenue
Oak Park, IL 60302
1660 L Street, NW, Suite 301
Washington, DC 20036
Little People of America, Inc.
250 El Camino Real
Tustin, CA 92780
Restricted Growth Association
PO Box 1024
Peterborough, Intl PE1 9GX
Tel: 0300 111 1970
Fax: 0300 111 2454
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
One AMS Circle
Bethesda, MD 20892-3675
Coalition for Heritable Disorders of Connective Tissue (CHDCT)
4301 Connecticut Avenue, NW Suite 404
Washington, DC 20008
MUMS National Parent-to-Parent Network
150 Custer Court
Green Bay, WI 54301-1243
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
PO Box 241956
Los Angeles, CA 90024
For a Complete Report
This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email firstname.lastname@example.org
Last Updated: 9/24/2007
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