Fletcher Allen, a Vermont university hospital and medical center, serves all of
Vermont and the northern New York region. Located in Burlington, Fletcher Allen is a regional, academic healthcare center and teaching hospital in alliance with the University of Vermont.
Cryotherapy for Abnormal Cervical Cell Changes
Cryotherapy destroys abnormal tissue on the cervix by freezing it. Cryotherapy destroys some normal tissue along with the abnormal tissue. During cryotherapy, liquid carbon dioxide (CO2), which is very cold, circulates through a probe placed next to the abnormal tissue. This freezes the tissue for 2 to 3 minutes. It may be allowed to thaw and then be refrozen for another 2 to 3 minutes. A single freeze treatment for 5 minutes may also be used.
Cryotherapy causes some discomfort. Most women feel a sensation of cold and a little cramping, and sometimes a sense of warmth spreads to the upper body and face.
Cryotherapy is not adequate treatment if abnormal cells are high in the cervical canal. In that case, another treatment, such as a cone biopsy, will be recommended instead of cryotherapy.
How it is done
Cryotherapy is usually done at your doctor's office, a clinic, or a hospital as an outpatient procedure (you do not have to spend a night in the hospital).
You will need to take off your clothes below the waist and drape a paper or cloth covering around your waist. You will then lie on your back on an exam table with your feet raised and supported by footrests (stirrups). Your doctor will insert an instrument with curved blades (speculum) into your vagina. The speculum gently spreads apart the vaginal walls, allowing the inside of the vagina and the cervix to be examined.
Your doctor may use medicine to numb the cervix (cervical block).
What To Expect After Surgery
Most women are able to return to their normal activity level the day after the cryotherapy procedure.
- A watery vaginal discharge will occur for about 2 to 3 weeks.
- Pads should be used instead of tampons for 2 to 3 weeks.
- Sexual intercourse should be avoided for 2 to 3 weeks.
- Douching should not be done for 2 to 3 weeks.
When to call your doctor
Call your doctor if you have any of the following symptoms:
- A fever
- Moderate to heavy bleeding (more than you would usually have during a menstrual period)
- Increasing pelvic pain
- Bad-smelling or yellowish vaginal discharge, which may point to an infection
Why It Is Done
Cryotherapy is done when abnormal Pap test results have been confirmed by colposcopy. If the results of endocervical curettage do not show abnormal tissue high inside the cervical canal, then cryotherapy can be used to treat the abnormal tissue seen with colposcopy.
How Well It Works
Cryotherapy is an effective method for destroying abnormal cervical tissue, depending on the size, depth, and type of abnormal tissue. Studies have had differing results, but cryotherapy appears to destroy all of the abnormal tissue in 77% to 96% of cases.1
Destruction of the abnormal tissue will not be complete if the abnormal cells are too deep in the cervical tissue.
What To Think About
If you have cryotherapy, you need regular follow-up Pap tests. Pap tests should be repeated every 4 to 6 months or as recommended by your doctor. After several Pap test results are normal, you and your doctor can decide how often to schedule future Pap tests.
Cryotherapy is not a treatment for cervical cancer.
Last Revised: December 28, 2010
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