etidronate

Pronunciation: e ti DROE nate

Brand: Didronel

Etidronate 400 mg-MYL

oblong, white, imprinted with ED400, G

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Didronel 200 mg

rectangular, white, imprinted with P&G, 402

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Didronel 400 mg

oblong, white, imprinted with NE, 406

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Etidronate 200 mg-MYL

rectangular, white, imprinted with ED 200, G

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What is the most important information I should know about etidronate?

Multum donot

You should not take this medicine if you have a condition called osteomalacia (softening of the bones), or a problem with the movement of muscles in your esophagus.

What is etidronate?

Etidronate is in a group of medicines called bisphosphonates (bis FOS fo nayts). It alters the cycle of bone formation and breakdown in the body.

Etidronate is used to treat Paget's disease, and to treat conditions of irregular bone growth due to hip fracture or spinal cord injury.

Etidronate may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking etidronate?

Multum donot

You should not take this medicine if you have a condition called osteomalacia (softening of the bones), or a problem with the movement of muscles in your esophagus.

To make sure etidronate is safe for you, tell your doctor if you have:

  • diarrhea;
  • a bone fracture;
  • trouble swallowing;
  • a stomach or esophageal ulcer or disease; or
  • kidney disease.

In rare cases, this medicine may cause bone loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work. The longer you use etidronate, the more likely you are to develop this condition.

Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids. Other risk factors include blood clotting disorders, anemia (low red blood cells), and a pre existing dental problem.

Talk with your doctor about the risks and benefits of using this medication.

Multum nopreg

FDA pregnancy category C. It is not known whether etidronate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Multum nobrfeed

It is not known whether etidronate passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I take etidronate?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Multum nocrush

Do not crush, chew, or suck the pill. Swallow it whole.

Multum water

Take each etidronate tablet with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking an etidronate tablet.

Multum donot

For at least the first 2 hours after taking etidronate, do not eat or drink anything other than plain water, and do not take any other medicines including vitamins or mineral supplements.

It is important to take etidronate regularly to get the most benefit.

Multum emt

If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using etidronate. You may need to stop using the medicine for a short time.

After you stop taking etidronate, you must stay off the medication for at least 90 days before starting etidronate therapy again.

Your doctor will need to check your progress while you are using etidronate.

Etidronate is only part of a complete program of treatment that may also include taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.

Multum rt

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include vomiting, numbness or tingly feeling around your mouth, fast or slow heart rate, muscle tightness or contraction, overactive reflexes.

What should I avoid while taking etidronate?

Multum nodairy

Avoid drinking milk or eating dairy products within 2 hours after taking etidronate. Also avoid taking supplements that contain calcium, magnesium, iron, or aluminum (such as in multivitamins with iron, and in many types of antacids).

What are the possible side effects of etidronate?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum calldoc

Stop using etidronate and call your doctor at once if you have:

  • painful or difficult swallowing;
  • severe heartburn, burning pain in your upper stomach, or coughing up blood;
  • severe joint, bone, or muscle pain;
  • jaw pain, numbness, or swelling;
  • severe diarrhea;
  • bone fracture; or
  • a red, blistering, peeling skin rash.

Common side effects may include:

  • mild diarrhea;
  • headache, confusion;
  • muscle cramps, joint pain; or
  • numbness or tingly feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect etidronate?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with etidronate, especially a blood thinner such as warfarin, Coumadin.

Other drugs may interact with etidronate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about etidronate.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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