Richard J. Solomon, MD

Education:

Training:

Residency

Fellowship

Specialty:

Certifications:

Academic Appointments:

Biography:

Dr. Richard Solomon trained in Internal Medicine at the University of California and in Nephrology at Beth Israel Hospital in Boston, MA.  He joined the faculty of the University of Vermont in 2002.  Previously, he was the clinical director of the Nephrology unit at the Joslin Diabetes Center in Boston and the Medical Director of the Dialysis Program for the Beth Israel Deaconess Medical Center. He is an experienced clinical investigator with interests in hypertension, chronic kidney disease, acute renal failure, and electrolyte disorders. He is currently the Chief of the Nephrology Unit in the Department of Medicine at the University of Vermont and Fletcher Allen Health Care. He and his wife, Laurinda, a diabetes nurse educator, live in St. George.

Major Research Interests:

Prevention of chronic renal insufficiency through aggressive targeting of risk factors and use of innovative educational programs to engage patients in their own care.  He and his his wife piloted the PEAK program at the Beth Israel Medical Center and Joslin Diabetes Center that educated patients and their family on how to prevent loss of kidney function. In the area of acute renal failure, Dr. Solomon's work in contrast-induced nephropathy remains the pivotal standard for prophylaxis. He is currently working on the role of N-acetylcysteine on nitric oxide function in patients with renal disease. In the area of comparative physiology, Dr. Solomon identified natriuretic peptides as the prime mechanism of salt balance in sharks, mediated via a unique organ the rectal gland. This gland is physiologically similar to the thick ascending limb of the loop of Henle in the mammalian kidney.

Recent Grant Support

Grant Title:      A Phase IV, Prospective, Randomized, Active-Controlled, Double-Blind,
                      Double-Dummy, Multi-Center Study to Evaluate the Survival Benefits of
                      Zemplar Relative to Calcijex in Subjects with Stage V Chronic Kidney
                      Disease on Hemodialysis
Sponsor:         Abbott Laboratories
PI:                  Dr. Richard Solomon

Grant Title:      Aliskirein Therapy for T2DM with Nephropathy
Sponsor:         Norvartis
PI:                  Dr. Richard Solomon

Grant Title:      Collaborative Group Trials with Sulodexide for Patients with Diabetes and
                      Microalbuminuria and Proteinuria (2 protocols)
PI:                  Dr. Richard Solomon

Grant Title:      CORAL: Medical vs Interventional Treatment of Renal Artery Stenosis
Sponsor:         NIH
PI:                  Dr. Richard Solomon

Grant Title:      Effect of N-Acetylcysteine on Serum Creatinine and Cystatin C in Patients
                      with Chronic Kidney Disease
Sponsor:         FlowMedica
PI:                  Dr. Richard Solomon

Publications:

Representative Publications from a Total of 139

Solomon R.  The role of osmolality in the incidence of contrast induced nephropathy: a systematic review of angiographic contrast media in high risk patients.  Kidney Int 68, 2256-2263, 2005.

Solomon R.  Contrast-induced nephropathy: a meta-analysis of contrast medium in high risk patients.  J Inv Cardiol 17, 29D-30D, 2005.

Solomon R, Briguori C, Bettmann M.  Selection of contrast media.  Kidney Int 69, S39-S45, 2006.

Solomon R, Barrett B.  Follow-up on patients with contrast-induced nephropathy.  Kidney Int 69, S46-S50, 2006.

Solomon R, DerayG.  How to prevent contrast-induced nephropathy and manage risk patients: practical recommendations.  Kidney Int 69, S51-S53, 2006.

Solomon R, DuMouchel W.  Contrast media and nephropathy: findings from systematic analysis and FDA reports of adverse effects.  Investigative Radiology 41, 651-660, 2006.

Solomon R, Natarajan MK, Douce S, Sharma S, Staniloae CS, Katholi RE, Gelormini JL, Labinaz M, Moreyra AE.  The CARE (Cardiac Angiography in REally Imparied Patients) Study: A randomized, double-blind trial of contrast-induced nephropathy in high risk patients.  Circulation 115, 3189-3196, 2007.

Solomon R.  Contrast media nephropathy - how to diagnose and how to prevent?  Nephrol Dial Transplant, 2007, in press.

Solomon R.  Pratice point: The role of bicarbonate therapy for prophylaxis of contrast induced nephropathy.  Nature Clinical Practice Cardiovascular Medicine, 2007, in press.

Kraus M, Burkart J, Hegeman R, Solomon R, Coplon N.  A comparison of center-based versus home-based hemodialysis for patients with end-stage renal disease.  Hemodialysis International, 2008.