Friederike K. Keating, MD

Education:

Medical School
Georg-August-University Goettingen, Germany

Training:

Residency

Dept of Cardiology, Georg-August-University Goettingen, Germany
Winthrop-University Hospital, Mineola, NY
Chief Residency
Winthrop-University Hospital, Mineola, NY

Fellowship

Specialty:

Women’s Cardiovascular Disease
Non-Invasive Cardiology
Cardiovascular Imaging
Echocardiography

Certifications:

Academic Appointments:

Biography:

Dr. Keating brings a focus on women’s cardiovascular disease to the group. Broadly trained in Internal Medicine and Cardiology, she also has extensive experience in basic and translational research and dedication to teaching. Her scientific background includes a doctorate in medicine “summa cum laude” at the University of Goettingen, where she did electrophysiological work on stimulus-secretion coupling. She has since performed and published both basic and clinical studies in electrophysiology before shifting her research focus to translational work on platelet function in coronary artery disease. As the leader of the Women’s Cardiac Care program, she provides consultative and general cardiology services to women with cardiovascular diseases, including coronary artery disease, heart failure and heart disease in pregnancy. Dr. Keating currently serves on the Board of Directors of the Vermont chapter of the American Heart Association. With her two children and her husband, a Radiologist at Fletcher Allen Health Care, she lives in beautiful Jericho, Vermont.

Major Research Interests:

Active research projects include:

•  the influence of female gender and, in particular estrogen, on platelet function.
• the influence of transfusion of blood products on platelet function
• the influence of leukocyte activation and platelet activating factor released by activated leukocytes on platelet function

Publications:

Representative Publications

Schneider DJ, Keating FK, Baumann PQ, Whitaker DA, Sobel BE. Increased ability of tirofiban to maintain its inhibitory effects on the binding of fibrinogen to platelets in blood from patients with and without diabetes mellitus. Coron Artery Dis 2006 February;17(1):57-61.

F.K. Keating, H.L. Dauerman, D.A. Whitaker, B.E. Sobel, D.J. Schneider. Increased Expression of Platelet P-selectin and Formation of Platelet-Leukocyte Aggregates in Blood from Patients Treated with Unfractionated Heparin plus Eptifibatide Compared with Bivalirudin. Thromb Res (2006).

F.K. Keating, H.L. Dauerman, D.A. Whitaker, B.E. Sobel, D.J. Schneider. The effects of bivalirudin compared with those of unfractionated heparin plus eptifibatide on inflammation and thrombin generation and activity during coronary intervention. Coron Artery Dis. (2005): 401-5.

F.K. Keating, D.A. Whitaker, S.S. Kabbani, M.A. Ricci, B.E. Sobel, D.J. Schneider. Relation of augmented platelet reactivity to the magnitude of distribution of atherosclerosis. Am J Cardiol, 94 (2004):725-8.

F.K. Keating, D.A. Whitaker, B.E. Sobel, D.J. Schneider. Augmentation of inhibitory effects of glycoprotein IIb-IIIa antagonists in patients with diabetes. Thromb Res. 113 (2004):27-34

F.K. Keating, B.E. Sobel, D.J. Schneider. Effects of increased concentrations of glucose on platelet reactivity in healthy subjects and in patients with and without diabetes mellitus. Am J Cardiol. 92 (2003):1362-5.

F. von zur Muhlen, W. Quan, D.J. D'Agate, T.J. Cohen. A study of carotid sinus massage and head-up tilt table testing in patients with syncope and near-syncope.J Invasive Cardiol. 14 (2002): 477-82.

F. von zur Muhlen, C. Klass, H. Kreuzer, G. Mall, A. Giese, C.D. Reimers. Cardiac involvement in proximal myotonic myopathy. Heart 79 (1998): 619-21.

F. von zur Muhlen, B.-D. Gonska, H. Kreuzer.  Inhibition of the voltage-dependent calcium current by external ATP in hamster ventricular cardiomyocytes. Am. J. Physiol. 273 (1997): H250-56.

F. von zur Muhlen, R. Penner. A GTP analogue induces calcium release but not secretion in rat mast cells. Int. Arch. Allergy Appl. Immunol. 94 (1991), 74-75.

F. von zur Muhlen, F. Eckstein, R. Penner. Guanosine 5'-[ß-thio]triphosphate selectively activates calcium signalling in mast cells. Proc. Natl. Acad. Sci. USA 88 (1991), 926-930.